AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 49(4), 1993, pp. 513-519
Copyright © 1993 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sein, K. K.
Right arrow Articles by Aikawa, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sein, K. K.
Right arrow Articles by Aikawa, M.

Sequestration Pattern of Parasitized Erythrocytes in Cerebrum, Mid-Brain, and Cerebellum of Plasmodium Catneyi-Infected Rhesus Monkeys (Macaca Mulatta)

Kyaw Kyaw Sein, Arthur E. Brown, Yoshimasa Maeno, C. Dahlem Smith, Kevin D. Corcoran, Pranee Hansukjariya, H. Kyle Webster AND Masamichi Aikawa
Institute of Pathology, Case Western Reserve University, Cleveland, Ohio; U.S. Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Six rhesus monkeys (Macaca mulatta) infected with Plasmodium coatneyi were studied for parasitized red blood cell (PRBC) sequestration in microvessels of the brain. The degree of PRBC sequestration is different in the cerebral, mid-brain, and cerebellar microvessels, with sequestration occurring preferentially in the cerebellum. This pattern resembles that of PRBC sequestration in cerebral and cerebellar microvessels in human falciparum malaria. The morphologic appearance of sequestered cells under light and electron microscopy as well as the PRBC sequestration pattern bolsters the contention that the rhesus monkey infected with P. coatneyi is an appropriate primate model for the experimental study of human cerebral malaria.




This article has been cited by other articles:


Home page
 Am J Trop Med HygHome page
A. MORENO, A. GARCIA, M. CABRERA-MORA, E. STROBERT, and M. R. GALINSKI
DISSEMINATED INTRAVASCULAR COAGULATION COMPLICATED BY PERIPHERAL GANGRENE IN A RHESUS MACAQUE (MACACA MULATTA) EXPERIMENTALLY INFECTED WITH PLASMODIUM COATNEYI
Am J Trop Med Hyg, April 1, 2007; 76(4): 648 - 654.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1993 by the American Society of Tropical Medicine and Hygiene.