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Am. J. Trop. Med. Hyg., 49(2), 1993, pp. 189-191
Copyright © 1993 by The American Society of Tropical Medicine and Hygiene

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Serologic Response to Helicobacter pylori among Children and Teenagers in Northern Chile

Robert G. Russell, Steven S. Wasserman, J. Michael O'Donnoghue, David N. Taylor, John Boslego, Julio Garcia Moreno, Robert J. Hopkins, Louis J. Detolla AND J. Glenn Morris, Jr
Program in Comparative Medicine and Department of Pathology, Division of Geographic Medicine, Department of Medicine, and Division of Infectious Diseases, University of Maryland School of Medicine, Baltimore, Maryland; Department of Veterans Affairs Medical Center, Baltimore, Maryland; Department of Bacterial Diseases, Walter Reed Army Institute of Research, Washington, District of Columbia; Instituto de Salud Publica, AVDA Marathon 100, Santiago, Chile

The serologic response to Helicobacter pylori was determined in 388 children and teenagers living in Iquique, Chile by using an IgG enzyme-linked immunosorbent assay. Serum antibody levels, as measured by optical density, correlated strongly with age. Increases in the mean antibody level were seen primarily after age five, with rates of seropositivity increasing to ≥ 70% among teenagers. The reasons for this age-related pattern of acquisition of infection remain to be determined.




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K. O'Rourke, K. J. Goodman, M. Grazioplene, T. Redlinger, and R. S. Day
Determinants of Geographic Variation in Helicobacter pylori Infection among Children on the US-Mexico Border
Am. J. Epidemiol., October 15, 2003; 158(8): 816 - 824.
[Abstract] [Full Text] [PDF]


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Copyright © 1993 by the American Society of Tropical Medicine and Hygiene.