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Am. J. Trop. Med. Hyg., 47(1_Suppl), 1992, pp. 2-7
Copyright © 1992 by The American Society of Tropical Medicine and Hygiene

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Tumor Necrosis Factor in the Malnutrition (Cachexia) of Infection and Cancer

Kevin J. Tracey AND Anthony Cerami
Division of Neurosurgery, Cornell University Medical Center, New York, New York; Picower Institute for Medical Research, Manhasset, New York

This review presents a history of tumor necrosis factor, considers the biology of this pleiotropic mediator, and summarizes the evidence that implicates it as a mediator of cachexia.






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Copyright © 1992 by the American Society of Tropical Medicine and Hygiene.