AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 47(1), 1992, pp. 61-69
Copyright © 1992 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chen, W.-R.
Right arrow Articles by Tesh, R. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chen, W.-R.
Right arrow Articles by Tesh, R. B.

A new Genotype of Japanese Encephalitis Virus from Indonesia

Woan-Ru Chen, Rebeca Rico-Hesse AND Robert B. Tesh
Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut

Primer-extension sequencing of the RNA template of polio, dengue, Rift Valley fever, and Japanese encephalitis (JE) viruses has provided new information on their geographic distribution, origin, and evolution. In a previous study of 46 diverse JE virus strains, we demonstrated the existence of three distinct JE genotypes in Asia. We now report the occurrence of a fourth genotype. In the present study, 19 JE virus isolates, representing various geographic regions of Asia and a 50-year time span, were compared with each other and with Murray Valley encephalitis, West Nile, and Kunjin viruses. Twelve of the JE strains from the Indonesian Archipelago and the Philippines had not been previously examined; the remainder were representatives of the three previously identified genotypes. Two hundred forty nucleotides from the pre-M gene region of the virus were used in these comparisons. Using 12% divergence as a cut-off point, the 19 JE strains fell into four distinct genotypic groups; maximum divergence across the comparison region was 21%. The newly recognized fourth genotype was comprised of five Indonesian isolates that were 7% divergent from the rest of the JE viruses.




This article has been cited by other articles:


Home page
 J. Virol.Home page
A. P. Goncalvez, C.-H. Chien, K. Tubthong, I. Gorshkova, C. Roll, O. Donau, P. Schuck, S. Yoksan, S.-D. Wang, R. H. Purcell, et al.
Humanized Monoclonal Antibodies Derived from Chimpanzee Fabs Protect against Japanese Encephalitis Virus In Vitro and In Vivo
J. Virol., July 15, 2008; 82(14): 7009 - 7021.
[Abstract] [Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
G. N. Sapkal, N. S. Wairagkar, V. M. Ayachit, V. P. Bondre, and M. M. Gore
Detection and Isolation of Japanese Encephalitis Virus From Blood Clots Collected During the Acute Phase of Infection
Am J Trop Med Hyg, December 1, 2007; 77(6): 1139 - 1145.
[Abstract] [Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
M. Saito, K. Taira, K. Itokazu, and N. Mori
Recent Change of the Antigenicity and Genotype of Japanese Encephalitis Viruses Distributed on Okinawa Island, Japan
Am J Trop Med Hyg, October 1, 2007; 77(4): 737 - 746.
[Abstract] [Full Text] [PDF]

Home page
 J. Gen. Virol.Home page
H. Y. Wang, T. Takasaki, S. H. Fu, X. H. Sun, H. L. Zhang, Z. X. Wang, Z. Y. Hao, J. K. Zhang, Q. Tang, A. Kotaki, et al.
Molecular epidemiological analysis of Japanese encephalitis virus in China
J. Gen. Virol., March 1, 2007; 88(3): 885 - 894.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1992 by the American Society of Tropical Medicine and Hygiene.