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Am. J. Trop. Med. Hyg., 46(6), 1992, pp. 732-736
Copyright © 1992 by The American Society of Tropical Medicine and Hygiene

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Evaluation of Eosinophiluria in the Diagnosis of Schistosomiasis Hematobium: a Field-Based Study

Isam A. Eltoum, Suad M. Suliaman, Babiker M. Ismail, Ahmed I. A. Ismail, Magdi M. M. Ali AND Mamoun M. A. Homeida
Departments of Pathology and Medicine, Faculty of Medicine, Khartoum, Sudan; Bilharzia Research Unit, National Health Laboratory, Khartoum, Sudan; Sudan-MRC/NIH Medical Parasitology Project, Khartoum, Sudan

Using Hansel's stain, eosinophiluria greater than 5% of total urinary white blood cells was found in 59% of a randomly selected population sample in an area endemic for schistosomiasis hematobium. The prevalence and mean level of eosinophiluria were significantly higher in infected subjects than in noninfected subjects (P < 0.05). The sensitivity (80%), specificity (86%), and positive predictive value (82%) of eosinophiluria as a diagnostic index for schistosomiasis hematobium were significantly higher (Youdin index 0.66; P < 0.05) than those of proteinuria, hematuria, and leukocyturia taken singly or in combination. However, unlike the latter three measurements, this method involves microscopy. There is a great need for a chemical method for measuring eosinophiluria.







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Copyright © 1992 by the American Society of Tropical Medicine and Hygiene.