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Herpes Simplex Virus Type 2 Antibodies: High Prevalence in Monogamous Women in Costa Rica

We studied the prevalence of antibody to Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) in 766 randomly selected Costa Rican women 25–59 years of age in a national household survey in 1984–1985. Overall, 97.1% were seropositive for HSV-1 and 39.4% for HSV-2. Only 1.1% of HSV-2 seropositive women gave a history of symptomatic genital herpes. HSV-2 virus antibody increased with age and with the number of lifetime sexual partners. HSV-2 seroprevalence among women who reported only 1 lifetime sexual partner was almost twice as high as the prevalence among women who denied sexual experience (30.5% vs. 17.7%) and reached 79.2% among women with 4 partners. HSV-2 seroprevalence was lower among women whose partners used condoms: 28.9% for those who had used condoms for at least 2 years vs. 44.3% for those who never used condoms.

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				M. Pickles, A. M Foss, P. Vickerman, K. Deering, S. Verma, E. Demers, R. Washington, B. Ramesh, S. Moses, J. Blanchard, et al. Interim modelling analysis to validate reported increases in condom use and assess HIV infections averted among female sex workers and clients in southern India following a targeted HIV prevention programme Sex Transm Inf, February 1, 2010; 86(Suppl_1): i33 - i43. [Abstract] [Full Text] [PDF]