AJTMH Tropical Medicine and Hygiene News
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 39(6), 1988, pp. 607-610
Copyright © 1988 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lvov, D. K.
Right arrow Articles by Calisher, C. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lvov, D. K.
Right arrow Articles by Calisher, C. H.

Identity of Karelian Fever and Ockelbo Viruses Determined by Serum Dilution-Plaque Reduction Neutralization Tests and Oligonucleotide Mapping

Dmitri K. Lvov, Elena A. Vladimirtseva, Alexander M. Butenko, N. Karabatsos*, Dennis W. Trent* AND Charles H. Calisher*
D. I. Ivanovsky Institute of Virology, USSR Academy of Medical Sciences, 123098 Moscow, USSR
* Division of Vector-Borne Viral Diseases, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Fort Collins, Colorado 80522

The causative agents of Ockelbo disease in Sweden, Pogosta disease in Finland, and Karelian fever in the USSR have been attributed to alphaviruses (family Togaviriade) related to Sindbis virus. We compared prototypes Sindbis, Ockelbo, and Karelian fever viruses by neutralization tests. We also analyzed oligonucleotide fingerprint maps of prototypes Ockelbo and Karelian fever viruses and a strain of Sindbis virus from Czechoslovakia. The results indicate that Ockelbo and Karelian fever viruses are essentially identical and suggest that Ockelbo disease, Pogosta disease, and Karelian fever are synonyms for the same disease.

Accepted for publication July 5, 1988.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1988 by the American Society of Tropical Medicine and Hygiene.