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Am. J. Trop. Med. Hyg., 39(5), 1988, pp. 440-444
Copyright © 1988 by The American Society of Tropical Medicine and Hygiene

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Amebic Liver Abscess and Circulating Immune Complexes of Entamoeba Histolytica Proteins

Brij Mohan Gandhi, Mohammad Irshad, Subrat Kumar Acharya AND Badri Nath Tandon
Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110029, India

An enzyme-linked immunosorbent assay (ELISA) has been developed to detect amebic antigen in polyethylene-glycol-precipitable circulating immune complexes. Seventy-nine percent of 191 patients with amebic liver abscesses and 46% of 26 Entamoeba histolytica cyst passers had positive tests. None of the samples from 43 apparently healthy controls, 8 patients with past amebic liver abscesses or 31 patients with Giardia lamblia infections were positive. One patient out of 32 with viral hepatitis and 1 patient out of 27 with intestinal tuberculosis had positive tests.

Accepted for publication June 23, 1988.






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Copyright © 1988 by the American Society of Tropical Medicine and Hygiene.