HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Beaver, P. C. Search for Related Content PubMed PubMed Citation Articles by Beaver, P. C.

Light, Long-Lasting Necator Infection in a Volunteer

A Necator infection produced by percutaneous exposure of a volunteer to three larvae was followed with periodic egg counts for 4 months beyond 18 years when passage of eggs in the feces ceased permanently. During the 2nd year of infection, there was unintentional exposure to two additional larvae. Egg counts per gram of feces (EPG) were approximately 1,000 during the 1st year, 1,500 over the next 5 years, and 200 over the final 3 years, during which time there were 6 periods of approximately 1 month each when Kato thick-smear examinations revealed no eggs. During 6 of the 1st 14 years, when egg counts were done by the standard direct smear method, up to 37% of the eggs were infertile. Based on the assumption that two female worms were present during the 1st year, three during the next 3 years or more, and only one during the final 3 years, the estimated output per female in this light infection was 500 EPG in the worm's prime of life, and less than 200 EPG in the final year of the 17 or 18 year life span.

Accepted for publication April 8, 1988.

This article has been cited by other articles:

				Y. Cho, B. F. Jones, J. J. Vermeire, L. Leng, L. DiFedele, L. M. Harrison, H. Xiong, Y.-K. A. Kwong, Y. Chen, R. Bucala, et al. Structural and Functional Characterization of a Secreted Hookworm Macrophage Migration Inhibitory Factor (MIF) That Interacts with the Human MIF Receptor CD74 J. Biol. Chem., August 10, 2007; 282(32): 23447 - 23456. [Abstract] [Full Text] [PDF]

				K. MORTIMER, A. BROWN, J. FEARY, C. JAGGER, S. LEWIS, M. ANTONIAK, D. PRITCHARD, and J. BRITTON DOSE-RANGING STUDY FOR TRIALS OF THERAPEUTIC INFECTION WITH NECATOR AMERICANUS IN HUMANS Am J Trop Med Hyg, November 1, 2006; 75(5): 914 - 920. [Abstract] [Full Text] [PDF]