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Am. J. Trop. Med. Hyg., 35(1), 1986, pp. 56-60
Copyright © 1986 by The American Society of Tropical Medicine and Hygiene

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Infection of Mosquitoes with Plasmodium vivax from Chimpanzees Using Membrane Feeding

William E. Collins, Harold M. McClure*, R. Brent Swenson*, Philip C. Mehaffey AND Jimmie C. Skinner
Malaria Branch, Division of Parasitic Diseases, Center for Infectious Diseases, Centers for Disease Control, U.S. Department of Health and Human Services, Atlanta, Georgia 30333 and Division of Pathobiology and Immunobiology and Division of Veterinary Medicine ,
* Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia 30322

Six splenectomized chimpanzees were infected with the Chesson or the North Korean strains of Plasmodium vivax. Heparinized blood taken from the animals was fed to approximately 45,000 mosquitoes using parafilm membranes. High-level mosquito infections were obtained with the blood from 4 animals. One animal infected mosquitoes only at a very low level. The other chimpanzee failed to produce a parasitemia high enough to warrant mosquito feeding.

Accepted for publication July 23, 1985.




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Y Charoenvit, W. Collins, T. Jones, P Millet, L Yuan, G. Campbell, R. Beaudoin, Broderson JR, and S. Hoffman
Inability of malaria vaccine to induce antibodies to a protective epitope within its sequence
Science, February 8, 1991; 251(4994): 668 - 671.
[Abstract] [PDF]




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Copyright © 1986 by the American Society of Tropical Medicine and Hygiene.