AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 35(1), 1986, pp. 162-166
Copyright © 1986 by The American Society of Tropical Medicine and Hygiene

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Lobomycosis in Western Brazil: Report of a Clinical Trial with Ketoconazole*

Dale N. Lawrence AND Libero Ajello
Division of Host Factors and Division of Mycotic Diseases, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S Department of Health and Human Services, Atlanta, Georgia 30333

We report a case of chronic lobomycosis, contracted by a rural resident of the westernmost Brazilian state, Acre, and substantiate that western Amazonia is now an endemic area for Loboa loboi. No changes in lesion morphology resulted from a prolonged course of oral therapy with ketoconazole administered in an attempt to prevent the progressive and destructive extension of the disease.

Accepted for publication July 1, 1985.


* Address reprint requests to: Libero Ajello, Ph.D., Division of Mycotic Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 30333.







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Copyright © 1986 by the American Society of Tropical Medicine and Hygiene.