HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Wallis, G. P. Articles by Tabachnick, W. J. Search for Related Content PubMed PubMed Citation Articles by Wallis, G. P. Articles by Tabachnick, W. J.

Selection for Susceptibility and Refractoriness of Aedes Aegypti to Oral Infection with Yellow Fever Virus

G. P. Wallis^*, T. H. G. Aitken, B. J. Beaty, L. Lorenz, G. D. Amato^* AND W. J. Tabachnick

^* Department of Biology
Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut 06511
Department of Biology, Loyola University, 6525 North Sheridan Road, Chicago, Illinois 60626

Artificial selection on strains of Aedes aegypti showing susceptibility and refractoriness to oral infection with yellow fever virus (YFV) suggests that there is a significant genetic component to this trait. Using a population with an average susceptibility of 15%, inbreeding of isofemale lines followed by individual selection produced susceptible (29% infected) and refractory (11% infected) lines. The difference between lines was largely apparent before individual selection, which failed to increase/decrease susceptibility significantly. The findings suggest that very few loci with a major bearing on the trait segregated genetic variation in the original population sample, and that non-genetic factors also play a major role in determining whether or not Ae. aegypti females become infected with YFV.

Accepted for publication June 18, 1985.

This article has been cited by other articles:

				L. Urdaneta-Marquez, C. Bosio, F. Herrera, Y. Rubio-Palis, M. Salasek, and W. C. Black IV Genetic Relationships among Aedes aegypti Collections in Venezuela as Determined by Mitochondrial DNA Variation and Nuclear Single Nucleotide Polymorphisms Am J Trop Med Hyg, March 1, 2008; 78(3): 479 - 491. [Abstract] [Full Text] [PDF]