HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Rodhain, F. Articles by Hannoun, C. Search for Related Content PubMed PubMed Citation Articles by Rodhain, F. Articles by Hannoun, C.

Arboviruses and Lemurs in Madagascar: Experimental Infection of Lemur Fulvus with Yellow Fever and West Nile Viruses^*

Francois Rodhain^**, Jean-Jacques Petter, Roland Albignac, Pierre Coulanges AND Claude Hannoun^**

^** Laboratoire des Arbovirus, Unité d'Ecologie Virale, Institut Pasteur, 75015 Paris, France
Laboratoire d'Ecologie Générale, Museum National d'Histoire Naturelle, Brunoy, France
Laboratoire d'Ecologie Animale, Faculté des Sciences, 25035 Besançon, France
Institut Pasteur de Madagascar, B.P. 1274, Antananarivo, Madagascar

In previous serological surveys of lemurs in Madagascar, antibodies against flaviviruses were frequently detected. To examine the epidemiological role of Lemur fulvus, experimental infections with yellow fever (YF) virus and West Nile (WN) virus were performed. YF and WN infections were clinically unapparent. A 3 to 4-day-long viremia, with moderate levels was observed with YF virus. WN virus, especially the strain isolated in Madagascar, provoked a 4 to 6-day-long viremia sufficient to infect Aedes aegypti. In all experiments, the antibody response was studied during the following weeks by 3 methods. The results led to the conclusion that Malagasy lemurs could act as amplifying hosts for WN virus present in Madagascar, and as hosts for YF virus if it were introduced on the island. The epidemiological role of these primates is discussed according to their ecology and their contact with potential mosquito vectors in forest areas of Madagascar.

Accepted for publication October 22, 1984.

^* These investigations were supported by the Institut National de la Sante et de la Recherche Medicale, contract C.R.L. No. 79.4.440.8.

This article has been cited by other articles:

				K. Sondgeroth, B. Blitvich, C. Blair, J. Terwee, R. Junge, M. Sauther, and S. VandeWoude ASSESSING FLAVIVIRUS, LENTIVIRUS, AND HERPESVIRUS EXPOSURE IN FREE-RANGING RING-TAILED LEMURS IN SOUTHWESTERN MADAGASCAR J. Wildl. Dis., January 1, 2007; 43(1): 40 - 47. [Abstract] [Full Text] [PDF]

				C. G. HAYES West Nile Virus: Uganda, 1937, to New York City, 1999 Ann. N.Y. Acad. Sci., December 1, 2001; 951(1): 25 - 37. [Abstract] [Full Text] [PDF]