AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 34(1), 1985, pp. 119-123
Copyright © 1985 by The American Society of Tropical Medicine and Hygiene

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Regression of Splenomegaly and Hepatomegaly in Children Treated for Schistosoma haematobium Infection

Lani S. Stephenson*, Michael C. Latham*, Stephen N. Kinoti{dagger} AND Martin L. Oduori{ddagger}
* Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853
{dagger} Medical Research Center, a Department of the Kenya Medical Research Institute, P.O. Box 20752, Nairobi, Kenya
{ddagger} Ministry of Health, P.O. Box 30016, Nairobi, Kenya

During a study in Kenya of the relationships between Schistosoma haematobium infection and anemia and growth, evidence was found to suggest that this infection was associated with splenomegaly in children, and that both splenomegaly and hepatomegaly regressed in children treated for urinary schistosomiasis, compared with a placebo group. These results imply that S. haematobium is partially responsible for the splenomegaly and hepatomegaly found in this malarious area, and that treatment for S. haematobium may cause a significant regression of splenomegaly and hepatomegaly in children.

Accepted for publication June 18, 1984.







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Copyright © 1985 by the American Society of Tropical Medicine and Hygiene.