AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 33(6), 1984, pp. 1270-1271
Copyright © 1984 by The American Society of Tropical Medicine and Hygiene

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Amyloidosis in Experimental Tegumentary Leishmaniasis in Mice*

Elizabeth G. O. Barbosa-Santos{dagger}, S. C. Gonçalves da Costa{dagger} AND A. Alencar{ddagger}
{dagger} Departamento de Protozoologia
{ddagger} Hospital Evandro Chagas, Instituto Oswaldo Cruz, Caixa Postal 926, Rio de Janeiro, Brazil

Renal and hepatosplenic amyloidosis was found in chronic cutaneous leishmaniasis in mice infected with 106 purified amastigotes from lesions produced by the H21 strain of Leishmania mexicana amazonensis. After 1 year a progressive lesion leading to metastasis was observed in most animals.

Accepted for publication April 5, 1984.


* Supported by CNPq-SIP/08-142.






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Copyright © 1984 by the American Society of Tropical Medicine and Hygiene.