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Am. J. Trop. Med. Hyg., 33(1), 1984, pp. 182-184
Copyright © 1984 by The American Society of Tropical Medicine and Hygiene

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Glucose-6-Phosphate Dehydrogenase Deficiency in Southeast Asian Refugees Entering the United States

Ira K. Schwartz, William Chin, Jeffrey Newman AND Jacquelin M. Roberts
Division of Parasitic Diseases, Center for Infectious Diseases, and Division of Quarantine, Center for Prevention Services, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inherited disorder of red blood cell metabolism. Affected individuals may suffer a severe hemolytic crisis when treated with primaquine, an antimalarial. A survey of 966 male Southeast Asian refugees determined that 50 (5.2%) were G6PD-deficient. This prevalence suggests that a G6PD assay should be performed prior to primaquine therapy in this high-risk population.

Accepted for publication August 5, 1983.






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Copyright © 1984 by the American Society of Tropical Medicine and Hygiene.