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Am. J. Trop. Med. Hyg., 32(4), 1983, pp. 723-726
Copyright © 1983 by The American Society of Tropical Medicine and Hygiene

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Single-Day Drug Treatment of Amebic Liver Abscess

R. Lasserre, N. Jaroonvesama, S. Kurathong AND C.-T. Soh
Roche Far East Research Foundation, Hong Kong, Siriraj Hospital, Bangkok, Thailand, Ramathibodi Hospital, Bangkok, Thailand, and Institute of Tropical Medicine, Yonsei University, Seoul, Korea

This double-blind trial was initiated to test, in a controlled study, the value of single-day drug treatment of amebic liver abscess. Patients were treated with 2 g either of ornidazole or tinidazole, two newly developed 5-nitroimidazole derivatives, given in two equal doses during the course of 1 day. A success rate of over 94% in the 72 patients from both treatment groups who were followed up for 6 months demonstrates the efficacy of the single-day drug treatment.

Accepted for publication October 29, 1982.






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Copyright © 1983 by the American Society of Tropical Medicine and Hygiene.