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Am. J. Trop. Med. Hyg., 32(3), 1983, pp. 621-623
Copyright © 1983 by The American Society of Tropical Medicine and Hygiene

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Growth and Transovarial Transmission of Chandipura Virus (Rhabdoviridae: Vesiculovirus) in Phlebotomus Papatasi*

Robert B. Tesh AND Govind B. Modi
Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, P. O. Box 333, New Haven, Connecticut 06510

Chandipura virus multipled in sand flies (Phlebotomus papatasi) following intrathoracic inoculation. Within 24 hours, mean virus titers in infected flies increased approximately 4 logs. Experimentally infected P. papatasi transmitted the virus by bite to newborn mice and by transovarial transmission to their progeny. Eight percent of the F1 offspring of experimentally infected female parents were infected with Chandipura virus.

Accepted for publication September 9, 1982.


* This work was supported in part by contract DAMD17-80-C-0178 from the U.S. Army Medical Research and Development Command.




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Copyright © 1983 by the American Society of Tropical Medicine and Hygiene.