AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 32(3), 1983, pp. 452-455
Copyright © 1983 by The American Society of Tropical Medicine and Hygiene

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A Simple Field Kit for the Determination of Drug Susceptibility in Plasmodium Falciparum

Phuc Nguyen-Dinh, Roc Magloire AND William Chin
Malaria Branch, Parasitic Diseases Division, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333, and Section de Recherches, Service National des Endemies Majeures, Ministère de la Santé, Republic of Haiti

A field kit has been developed which greatly simplifies the performance of the 48-hour in vitro test for drug resistance in Plasmodium falciparum. The kit uses an easily reconstituted lyophilized culture medium, and requires only a fingerprick blood sample. In parallel tests with 13 isolates of P. falciparum in Haiti, the new technique had a success rate equal to that of the previously described method, with comparable results in terms of parasite susceptibility in vitro to chloroquine and pyrimethamine.

Accepted for publication August 16, 1982.






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Copyright © 1983 by the American Society of Tropical Medicine and Hygiene.