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Am. J. Trop. Med. Hyg., 31(6), 1982, pp. 1294-1296
Copyright © 1982 by The American Society of Tropical Medicine and Hygiene

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Effect of Praziquantel on Antigenemia in Murine Schistosomiasis*

Joel K. Weltman
Division of Biomedical Sciences, Brown University, Providence, Rhode Island 02912

Abstract. A substantial portion (63%) of circulating schistosomal antigen was cleared from the serum of hyperinfected mice within 72 hours after treatment with the helminthocide, praziquantel. This result suggests that circulating antigen may be a diagnostically useful marker for active schistosomiasis.

Accepted for publication July 29, 1982.


* Supported by a grant from the Edna McConnell Clark Foundation.






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Copyright © 1982 by the American Society of Tropical Medicine and Hygiene.