HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Turell, M. J. Articles by Reeves, W. C. Search for Related Content PubMed PubMed Citation Articles by Turell, M. J. Articles by Reeves, W. C.

Stabilized Infection of California Encephalitis Virus in Aedes dorsalis, and its Implications for Viral Maintenance in Nature^*

Michael J. Turell, James L. Hardy AND William C. Reeves

Abstract. Three populations of Aedes dorsalis were selected which transmitted California encephalitis (CE) virus vertically to over 90% of their progeny. Infected progeny in these subpopulations transmitted virus at similar rates through five generations; females from the last generation transmitted virus by bite to suckling mice. These high rates of vertical transmission appeared to be due to the development of a stabilized infection with CE virus rather than to genetic selection for a more efficient transmitter or for a mutant strain of virus. In contrast, female Ae. dorsalis and Aedes melanimon infected by intrathoracic inoculation developed nonstabilized infections and transmitted virus vertically to approximately 20% of their progeny. The existence of stabilized infections of CE virus in vector populations and its implications for the natural history of CE virus and on the Fine and LeDuc model are discussed.

Accepted for publication April 7, 1982.

^* This study was supported in part by funds from the U.S. Army Medical Research and Development Command (Contract No. DAMD 17-77-C-7018), from the National Institute of Allergy and Infectious Diseases (Research Grant AI003028), from the Office of Naval Research, and by special funds for mosquito control research appropriated annually by the California Legislature.

Present address: Department of Arboviral Entomology, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland 21701.

This article has been cited by other articles:

				R. S. Rust, W. H. Thompson, C. G. Matthews, B. J. Beaty, and R. W.M. Chun Topical Review: La Crosse and Other Forms of California Encephalitis J Child Neurol, January 1, 1999; 14(1): 1 - 14. [Abstract] [PDF]