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Falciparum Malaria Acquired in the Area of the Thai-Khmer Border Resistant to Treatment with Fansidar®^*

Fansidar®, quinine, and combinations of the two were evaluated as therapy in 173 cases of falciparum malaria in Royal Thai Army soldiers. Falciparum malaria acquired in the area of the Thai-Khmer border, by military units under Fansidar prophylaxis, has proven refractory to Fansidar therapy. Concurrent use of a single drug as a routine chemoprophylactic and as first-line therapy appears to be inappropriate in this case. Feasible alternatives for either role, however, are not readily available.

Accepted for publication February 18, 1982.

^* Address reprint requests to: Librarian, AFRIMS, APO San Francisco 96346.