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Am. J. Trop. Med. Hyg., 31(5), 1982, pp. 1030-1037
Copyright © 1982 by The American Society of Tropical Medicine and Hygiene

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Mesenteronal Infection Threshold of an Epizootic Strain of Venezuelan Encephalitis Virus in Culex (Melanoconion) Taeniopus Mosquitoes and Its Implication to the Apparent Disappearance of This Virus Strain from an Enzootic Habitat in Guatemala

W. F. Scherer, E. W. Cupp, G. M. Dziem, R. J. Breener AND J. V. Ordonez
Department of Microbiology, Cornell University Medical College, 1300 York Avenue, New York, New York 10021, Department of Entomology, Cornell University, Ithaca, New York 14850, and Area of Biological Sciences, University of San Carlos Medical School, Guatemala, C.A.

Culex (Melanoconion) taeniopus is a vector of Venezuelan encephalitis (VE) virus at a marsh focus in Guatemala and has low mesenteronal thresholds for infection by and transmission of two enzootic strains of VE virus. In contrast, samples of natural populations and subsequent F2 and F4 generations of these mosquitoes have a high mesenteronal threshold for infection by an epizootic VE strain isolated at the same marsh during the end of the 1969 VE epidemic-equine epizootic. The resistance of Cu. (Mel.) taeniopus to mesenteronal infection by this VE strain probably represents a key factor in the apparent disappearance of epizootic VE virus from the marsh focus following the 1969 outbreak.

Accepted for publication February 24, 1982.







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Copyright © 1982 by the American Society of Tropical Medicine and Hygiene.