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Arbovirology—Then and Now^*

First of all, I want to thank the Charles Franklin Craig lecture Committee for inviting me here today. It's a great honor and one I shall always remember. Thanks also to all of you for showing up to hear me. And special thanks to my good friend, Dr. Thomas P. Monath, for his glowing, morale-raising introduction.

In the next 30 minutes or so I intend to give you a cursory view of arbovirology over the last 80 years, indicating the high points along the way which I feel have most strongly affected developments in this field. It will be biased, of course, in favor of mosquito-borne viruses, because that's all I know, and in favor of the Western Hemisphere, because that's where I'm from, but I hope I can be forgiven for that. Then in the wind-up, I'll present a number of basic concepts which attempt to explain, at least in part, why arboviruses behave the way they do and how they manage to survive.

^* Forty-sixth Annual Charles Franklin Craig Lecture delivered before the American Society of Tropical Medicine and Hygiene, San Juan, Puerto Rico, 19 November 1981.