AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 31(1), 1982, pp. 19-23
Copyright © 1982 by The American Society of Tropical Medicine and Hygiene

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A Longitudinal Study of Malaria Antibodies in a Malaysian Population

II. Follow-Up of Individuals

Henry M. Mathews AND Timothy J. Dondero, Jr.*
Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333, and U.S. Army Medical Research Unit, Institute for Medical Research, Kuala Lumpur, Malaysia

A cohort of 62 persons living in a malaria-endemic area was examined by serology and by blood film 14 times over a 56-week period. Serologic responses (indirect hemagglutination test) of the group as a whole reflected the malaria transmission as determined by blood slide examination. The serologic responses of individuals showed titer changes that were not always consistent with blood slide results. The use of chloroquine may have modified the host's immune response.

Accepted for publication May 29, 1981.


* Present address: Centers for Disease Control, Atlanta, Georgia 30333.






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Copyright © 1982 by the American Society of Tropical Medicine and Hygiene.