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Am. J. Trop. Med. Hyg., 31(1), 1982, pp. 14-18
Copyright © 1982 by The American Society of Tropical Medicine and Hygiene

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A Longitudinal Study of Malaria Antibodies in a Malaysian Population

I. Group Responses

Henry M. Mathews AND Timothy J. Dondero, Jr.*
Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333, and U. S. Army Medical Research Unit, Institute for Medical Research, Kuala Lumpur, Malaysia

The indirect hemagglutination test was used to measure malaria antibody levels in residents of an endemic area of Malaysia. Blood specimens were collected at 4-week intervals for a year. Seropositivity rates increased with age and number of episodes of malaria in young children. Although antibody levels were variable, titers tended to rise with parasitemia and fall in the absence of detected parasites. In general, the serologic indices tended to reflect the parasitologic findings.

Accepted for publication May 29, 1981.


* Present address: Centers for Disease Control, Atlanta, Georgia 30333.






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Copyright © 1982 by the American Society of Tropical Medicine and Hygiene.