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Am. J. Trop. Med. Hyg., 30(5), 1981, pp. 1116-1120
Copyright © 1981 by The American Society of Tropical Medicine and Hygiene

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Hemostatic Abnormalities Following Echis carinatus (Saw-Scaled Viper) Envenomation in the Rhesus Monkey*

K. S. Chugh, D. Mohanthy, Yash Pal, K. C. Das, N. K. Ganguly AND R. N. Chakravarty
Departments of Nephrology, Hematology, and Experimental Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Hemostatic abnormalities following lethal and sublethal doses of Echis carinatus venom were studied in a subhuman primate model. The observations suggest the occurrence of disseminated intravascular coagulation of varying magnitude within a few hours of envenomation. A procoagulant effect of the venom of Echis carinatus is likely to be the major cause of the disturbance in the hemostatic mechanism.

Accepted for publication December 6, 1980.


* Address reprint requests to: Dr. K. S. Chugh, Professor of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.






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Copyright © 1981 by the American Society of Tropical Medicine and Hygiene.