HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hoch, A. L. Articles by Pinheiro, F. P. Search for Related Content PubMed PubMed Citation Articles by Hoch, A. L. Articles by Pinheiro, F. P.

An Outbreak of Mayaro Virus Disease in Belterra, Brazil

III. Entomological and Ecological Studies^*

Alfred L. Hoch, Norman E. Peterson, James W. LeDuc AND Francisco P. Pinheiro

Results of entomological and vertebrate host investigations made during dual outbreaks of Mayaro (MAY) and yellow fever (YF) viruses in Belterra, Pará, Brazil in 1978 are reported. Over 9,000 insects representing 26 species were assayed in 396 pools for the presence of arboviruses. Pools of Haemagogus janthinomys Dyar yielded the only isolates of either MAY of YF virus. The minimum field infection rate for nine isolates of MAY virus from Hg. janthinomys was 1:82, and for two isolates of YF virus was 1:368. Analysis of collection data showed Hg. janthinomys to be attracted to man as a blood source and present in all habitats sampled, although most abundant in the forest canopy. Twelve hundred bird sera and 584 mammal sera were tested by hemagglutination-inhibition (HI) tests for antibody to MAY virus. Highest MAY antibody prevalence rates were found among marmosets (Callithrix argentata, 32 positive of 119 tested, 27%). Mayaro virus was also isolated from the blood of a sylvan marmoset captured at the peak of the MAY virus outbreak. Experimental infection of marmosets with MAY virus confirmed that a substantial viremia follows infection with this virus. Marmosets were also found with HI antibody to YF virus (5/119, 4%). The results presented indicate that Hg. janthinomys was the principal vector of both MAY and YF viruses and that marmosets were the main amplifying hosts for MAY virus, and perhaps for YF virus as well.

Accepted for publication July 12, 1980.

^* This program was conducted under the auspices of the Ministerio de Saúde Pública do Brasil. The research was conducted at the Instituto Evandro Chagas, Belém, Pará, Brazil, under PAHO Project BRA 4311 and supported by Research Contract Number DAMD 17-74-G-9378 from the U.S. Army Medical Research and Development Command, Office of the Surgeon General, Washington, D.C. The opinions contained herein are those of the authors and should not be construed as official or reflecting the views of the Department of the Army.

Address reprint requests to: Reprints Section, Division of Academic Affairs, Walter Reed Army Institute of Research, Washington, D.C. 20012.

Present address: U.S. Army, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D.C. 20012.

Present address: Universidade de Brasilia, Faculdade de Ciencias de Saúde, 70.910-Brasilia-D. Federal—Brazil.

Present address: Gorgas Memorial Laboratory, APO Miami 34002.

This article has been cited by other articles:

				A. M. POWERS, P. V. AGUILAR, L. J. CHANDLER, A. C. BRAULT, T. A. MEAKINS, D. WATTS, K. L. RUSSELL, J. OLSON, P. F. C. VASCONCELOS, A. T. DA ROSA, et al. GENETIC RELATIONSHIPS AMONG MAYARO AND UNA VIRUSES SUGGEST DISTINCT PATTERNS OF TRANSMISSION. Am J Trop Med Hyg, September 1, 2006; 75(3): 461 - 469. [Abstract] [Full Text] [PDF]