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Red Cells Containing Hemoglobin E do not Inhibit Malaria Parasite Development in Vitro

The development of three isolates of Plasmodium falciparum in normal (AA) and hemoglobin E (HbE)-containing red cells was studied by in vitro culture. No differences were observed in the abilities of AA, heterozygous AE and homozygous EE cells to support parasite growth under both reduced (17%) and hyperbaric (30%) oxygen tension.

Accepted for publication November 22, 1980.

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