HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Thomas, V. Articles by Leng, Y. P. Search for Related Content PubMed PubMed Citation Articles by Thomas, V. Articles by Leng, Y. P.

Assessment of the Sensitivity, Specificity, and Reproducibility of the Indirect Immunofluorescent Technique for the Diagnosis of Amebiasis

The indirect immunofluorescence (IIF) test was used to study antibody titers to Entamoeba histolytica in various manifestations of clinical amebiasis by comparing the results with parasitological and clinical data from confirmed cases. The sensitivity, specificity, and reproducibility of this test for diagnosis were also studied. A high degree of correlation was found between reactivity in the IIF test and confirmed cases of amebic liver abscess. A positivity rate of 96% in sera of confirmed cases of amebic liver abscess in the present study compares favorably with the results of other workers. The IIF test is very useful in the diagnosis of hepatic amebiasis but is less sensitive for amebic dysentery. The test could not be used to differentiate between hepatic amebiasis and amebic dysentery. The IIF test was insensitive for amebic colitis and of no diagnostic value. Specificity and reproducibility of the test were good, as shown by results obtained with sera from patients with parasitic infections other than amebiasis.

Accepted for publication May 3, 1980.