AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 3(3), 1954, pp. 481-489
Copyright © 1954 by The American Society of Tropical Medicine and Hygiene

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Erythrocyte Sensitizing Substances from Five Strains of Leptospirae1

R. Shih-Man Chang AND Dorothy E. McComb
Department of Microbiology, Harvard School of Public Health

Serologically active erythrocyte-sensitizing substances (ESS) have been isolated from leptospirae. A method is described for the determination of antibodies to leptospiral-ESS. By this method the ESS obtained from each of the five strains studied, L. canicola, L. icterohemorrhagiae, L. hebdomadis, L. pomona and L. autumnalis reacted identically, which suggests that these leptospiral-ESS are genus, not serotype, specific.


1 This project was supported in part by Grants (E29C5 and E553) from the Division of Research Grants of the National Institutes of Health, U.S.P.H.S.






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Copyright © 1954 by the American Society of Tropical Medicine and Hygiene.