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Antibodies against Col-SK Virus in Mexican Sera¹

Antibodies of high titer against Col-SK virus were found in approximately 30 per cent of a group of 77 human sera drawn from poliomyelitis cases, their contacts, or healthy individuals residing in a rural area of the State of Puebla in Mexico. Similar antibodies were found in approximately 5 per cent of a group of 54 human sera drawn from poliomyelitis cases, their contacts, or healthy individuals residing in the City of Puebla. There was good agreement between positive neutralization reactions and positive hemagglutination-inhibition tests. The age distribution of immune reactions against Col-SK virus was unlike that of neutralization reactions against Yale-SK virus but resembled that of positive Weil-Felix reactions through childhood and adolescence.

¹ Aided by a grant from the Sister Elizabeth Kenny Foundation.