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Transplacental Transmission of Venezuelan Equine Encephalitis Virus in Horses^*

Transplacental passage of Venezuelan equine encephalitis virus, epizootic strain P-676, occurred in four of nine fetuses studied. The mares were infected near term. Virus was recovered in high titer from fetal blood and organs, while no virus was detected in maternal blood but neutralizing antibodies were present. No evidence of in utero infection was found in two fetuses from mares infected with MF-8, another epizootic strain of Venezuelan equine encephalitis virus.

Accepted for publication November 17, 1980.

^* This work was supported in part by research grant No. 1RO1-AI-13478 from the National Institute of Allergy and Infectious Diseases.

Address reprint requests to: Gorgas Memorial Laboratory, Box 935, APO Miami 34002, ATTN: Dr. Gustavo Justines.