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Am. J. Trop. Med. Hyg., 29(2), 1980, pp. 265-268
Copyright © 1980 by The American Society of Tropical Medicine and Hygiene

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Antigenuria in St. Louis Encephalitis*

James P. Luby, F. Kevin Murphy, James N. Gilliam, Chil-Young Kang AND Rebecca Frank
Divisions of Infectious Diseases and Dermatology, Department of Internal Medicine and Department of Microbiology, The University of Texas Health Science Center, Dallas, Texas 75235

Patients with St. Louis encephalitis may have urinary tract symptoms when they develop manifestations related to involvement of the central nervous system. During 1976, 12 patients with St. Louis encephalitis were studied for the presence of antigenuria, and compared to controls. Although virus isolation attempts were negative indirect immunofluorescence, electron microscopy, and immune electron microscopy demonstrated the presence of viral antigen in urine. Further study of antigenuria in St. Louis encephalitis is needed to delineate the pathophysiology of the lower urinary tract symptoms and to determine whether this phenomenon might furnish the basis for a rapid diagnostic test for the disease.

Accepted for publication June 16, 1979.


* Address reprint requests to: James P. Luby, M.D., Division of Infectious Diseases, University of Texas Health Science Center, 5323 Harry Hines Boulevard, Dallas, Texas 75235.




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M. T. SIIRIN, T. DUAN, H. LEI, H. GUZMAN, A. P. A. T. DA ROSA, D. M. WATTS, S.-Y. XIAO, and R. B. TESH
CHRONIC ST. LOUIS ENCEPHALITIS VIRUS INFECTION IN THE GOLDEN HAMSTER (MESOCRICETUS AURATUS)
Am J Trop Med Hyg, February 1, 2007; 76(2): 299 - 306.
[Abstract] [Full Text] [PDF]


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Copyright © 1980 by the American Society of Tropical Medicine and Hygiene.