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Am. J. Trop. Med. Hyg., 28(5), 1979, pp. 885-889
Copyright © 1979 by The American Society of Tropical Medicine and Hygiene

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The Pattern and Nature of the Lymphocyte Population Response in Dengue Hemorrhagic Fever

Somnate Boonpucknavig, Chanida Lohachitranond AND Suchitra Nimmanitya
Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok 4, Thailand, and The Children's Hospital, Bangkok 4, Thailand

Eighty-eight specimens consisting of lymphocytes separated from peripheral blood samples from 76 patients with dengue hemorrhagic fever (DHF) were studied. The results revealed a significant increase in numbers of atypical lymphocytes and B lymphocytes, and a decrease in T lymphocytes by comparison with normal controls. Anti-T lymphocyte antibody was also detected in the serum of all patients with DHF. The greatest increments and decrements of the above were noted on the day of shock or of subsidence of fever.

Accepted for publication March 17, 1979.







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Copyright © 1979 by the American Society of Tropical Medicine and Hygiene.