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Am. J. Trop. Med. Hyg., 28(2), 1979, pp. 184-189
Copyright © 1979 by The American Society of Tropical Medicine and Hygiene

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Neurologic Complications Following the Treatment of Human Babesia Microti Infection with Diminazene Aceturate*

Trenton K. Ruebush, II, Robert H. Rubin, Edward R. Wolpow, Paul B. Cassaday AND Myron G. Schultz
Parasitic Diseases Division, Bureau of Epidemiology, Center for Disease Control, Public Health Service, U.S. Department of Health, Education, and Welfare, Atlanta, Georgia 30333, Infectious Disease Unit of the Medical Service and Neurology Service, Massachusetts General Hospital, Boston, Massachusetts 02114, Department of Medicine and Department of Neurology, Harvard Medical School, Boston, Massachusetts 02114, and Nantucket Cottage Hospital, Nantucket, Massachusetts 02554

A 65-year-old man infected with Babesia microti failed to respond to therapy with oral chloroquine phosphate. He was then successfully treated with diminazene aceturate, an experimental anti-protozoal agent. After his recovery from babesiosis, the patient developed acute idiopathic polyneuritis (Landry-Guillain-Barré Syndrome), which was probably related to his diminazene therapy.

Accepted for publication August 19, 1978.


* Address reprint requests to: Robert H. Rubin, M.D., Infectious Disease Unit, Massachusetts General Hospital, Fruit Street, Boston, Massachusetts 02114.






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Copyright © 1979 by the American Society of Tropical Medicine and Hygiene.