AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 27(6), 1978, pp. 1277-1278
Copyright © 1978 by The American Society of Tropical Medicine and Hygiene

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Partial Protection of Plasmodium Falciparum-Vaccinated Aotus Trivirgatus against a Challenge of a Heterologous Strain*

Wasim A. Siddiqui, Diane W. Taylor, Siu-Chow Kan, Kenton Kramer AND Suzanne Richmond-Crum
Department of Tropical Medicine and Medical Microbiology, University of Hawaii School of Medicine, Honolulu, Hawaii 96816

Two Aotus trivirgatus griseimenbra monkeys which had been immunized with the merozoite-enriched FUP strain of Plasmodium falciparum were protected against a primary challenge with the homologous strain. The results described here show that these two monkeys were protected against a subsequent challenge with a heterologous strain (FVO) of P. falciparum. The unimmunized control monkey died of FVO infection by day 18.

Accepted for publication June 24, 1978.


* Supported by Contract ta-C-1227 from the Agency for International Development, U.S. Department of State.






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Copyright © 1978 by the American Society of Tropical Medicine and Hygiene.