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Partial Protection of Plasmodium Falciparum-Vaccinated Aotus Trivirgatus against a Challenge of a Heterologous Strain^*

Two Aotus trivirgatus griseimenbra monkeys which had been immunized with the merozoite-enriched FUP strain of Plasmodium falciparum were protected against a primary challenge with the homologous strain. The results described here show that these two monkeys were protected against a subsequent challenge with a heterologous strain (FVO) of P. falciparum. The unimmunized control monkey died of FVO infection by day 18.

Accepted for publication June 24, 1978.

^* Supported by Contract ta-C-1227 from the Agency for International Development, U.S. Department of State.

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