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Am. J. Trop. Med. Hyg., 27(6), 1978, pp. 1192-1194
Copyright © 1978 by The American Society of Tropical Medicine and Hygiene

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Demonstration of a Common Antigen Between Schistosoma Mansoni and Fasciola Hepatica

Ronald P. Pelley AND George V. Hillyer
Division of Geographic Medicine, Department of Medicine, Case Western Reserve University and University Hospitals, Cleveland, Ohio 44106, and Department of Biology, University of Puerto Rico, Río Piedras, Puerto Rico 00931

The presence of a common antigen between Schistosoma mansoni eggs and Fasciola hepatica adult worms was demonstrated by utilizing an anti-S. mansoni adult worm antiserum. Although not one of the three major serologic S. mansoni egg antigens, its complete cross-reactivity suggests that serologic tests done with these crude antigenic extracts will result in many false-positive cases in areas where both parasites are endemic.

Accepted for publication June 17, 1978.






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Copyright © 1978 by the American Society of Tropical Medicine and Hygiene.