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Am. J. Trop. Med. Hyg., 27(6), 1978, pp. 1137-1147
Copyright © 1978 by The American Society of Tropical Medicine and Hygiene

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Streptocerciasis: Degeneration of Adult Dipetalonema Streptocerca in Man Following Diethylcarbamazine Therapy*

Wayne M. Meyers, Roger Moris, Ronald C. Neafie, Daniel H. Connor AND Jacques Bourland{dagger}
Department of Infectious and Parasitic Diseases Pathology, Armed Forces Institute of Pathology, Washington, D.C. 20306, and Iyonda, B.P. 1028, Mbandaka, Republic of Zaire

Thirty-three patients in Zaire with streptocerciasis were treated daily with diethylcarbamazine (DEC) for 21 days. Histopathologic studies of biopsy specimens from papules of skin established that during DEC treatment adult male and female Dipetalonema streptocerca die and degenerate. DEC may thus produce radical cures of streptocerciasis.

Accepted for publication May 6, 1978.


* The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.


{dagger} Present address: Damien Foundation, B.P. 774, Bujumbura, Republic of Burundi.






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Copyright © 1978 by the American Society of Tropical Medicine and Hygiene.