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Am. J. Trop. Med. Hyg., 27(5), 1978, pp. 905-909
Copyright © 1978 by The American Society of Tropical Medicine and Hygiene

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Circulating Non-Human Microfilaria in a Patient with Systemic Lupus Erythematosus*

Bruce M. Greene, Gilbert F. Otto AND William B. Greenough, III
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, and Department of Zoology, University of Maryland, College Park, Maryland 20742

A 12-yr-old girl with systemic lupus erythematosus requiring steroid therapy was found to have a circulating microfilaria during an exacerbation of her illness. Morphologically, the microfilaria does not correspond precisely with any previously described species, though similarities exist between the patient's microfilaria and those of Dipetalonema reconditum of the dog and D. interstitium of the grey squirrel. The organism reported here is probably an undescribed species from a wild mammal. Although the association may be merely coincidental, this case suggests that compromised immunity might have led to this unusual infection with a non-human filaria.

Accepted for publication March 4, 1978.


* Presented previously in part at the Heartworm Symposium '74, Auburn, Alabama, March 1974.







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Copyright © 1978 by the American Society of Tropical Medicine and Hygiene.