HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Thiermann, E. Articles by Olguín, J. Search for Related Content PubMed PubMed Citation Articles by Thiermann, E. Articles by Olguín, J.

A Comparative Study of Some Combined Treatment Regimens in Acute Toxoplasmosis in Mice^*

The effectiveness of five treatment regimens was compared in mice during acute and late infection with Toxoplasma gondii. Parasitic cure rates, as judged by failure of brain tissue from surviving mice to produce infection when inoculated into clean mice, were as follows: pyrimethamine + sulfamethoxypyridazine, 92%; clindamycin + sulfamethoxypyridazine, 75%; spiramycin + sulfamethoxypyridazine, 16.7%; trimethoprim + sulfamethoxazole, 16.7%; sulfamethoxypyridazine alone, 0%. Pyrimethamine + sulfamethoxypyridazine was the most effective combination against acute toxoplasmosis in mice.

Accepted for publication December 31, 1977.

^* Address reprint requests to: Dr. Werner Apt B., Professor of Parasitology, South Faculty of Medicine, Box 5277, Santiago 3, Chile.