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Am. J. Trop. Med. Hyg., 27(2), 1978, pp. 354-356
Copyright © 1978 by The American Society of Tropical Medicine and Hygiene

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Inhibition of Mitogen-Induced Lymphocyte Proliferative Responses by Quinine

Y. H. Thong AND Antonio Ferrante
Department of Paediatrics, University of Adelaide, The Adelaide Children's Hospital, North Adelaide, South Australia 5006

In vitro mitogen-induced proliferative responses of human lymphocytes were inhibited by concentrations of quinine normally attainable during therapy of malaria infections. The clinical implications of these findings are discussed.

Accepted for publication August 20, 1977.






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Copyright © 1978 by the American Society of Tropical Medicine and Hygiene.