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Am. J. Trop. Med. Hyg., 27(1), 1978, pp. 106-112
Copyright © 1978 by The American Society of Tropical Medicine and Hygiene

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Vibrio Parahaemolyticus Enterocolitis in Bangladesh: Report of an Outbreak*

James M. Hughes, John M. Boyce, A. R. M. A. Aleem, Joy G. Wells, A. S. M. Mizanur Rahman AND George T. Curlin
Bureau of Epidemiology, Center for Disease Control, Public Health Service, U.S. Department of Health, Welfare, and Education, Atlanta, Georgia 30333, and the Cholera Research Laboratory, Dacca, Bangladesh

In March 1974 eight men in Chandpur, Bangladesh, experienced an illness characterized by severe abdominal cramps, nausea, vomiting and bloody diarrhea with onset 20 min to 9 h (median 2.5 h) after eating one of two fish dishes at a restaurant. Rectal cultures from all eight grew Kanagawa-positive strains of Vibrio parahaemolyticus (serotype O3K5) that were negative in the Sereny test for invasiveness and the Y-1 adrenal cell and infant mouse assays for enterotoxin production. The short incubation, severity of abdominal cramps and grossly bloody stools distinguish this illness from that usually associated with V. parahaemolyticus infection in the United States.

Accepted for publication July 23, 1977.


* Address reprint requests to: James M. Hughes, M.D., Enteric Diseases Branch, Bacterial Diseases Division, Bureau of Epidemiology, Center for Disease Control, Atlanta, Georgia 30333.







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Copyright © 1978 by the American Society of Tropical Medicine and Hygiene.