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Am. J. Trop. Med. Hyg., 26(5), 1977, pp. 1052
Copyright © 1977 by The American Society of Tropical Medicine and Hygiene

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Correspondence

Louis H. Miller
Laboratory of Parasitic Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda, Maryland 20014

This letter was stimulated by the article by Tsang et al. on a coagulation Factor XIIa inhibitor from adult Schistosoma mansoni (Am. J. Trop. Med. Hyg., 26: 243–247, 1977). Since there is a limited literature on defining anticoagulants in helminthic infections, I felt it important to bring to the readers' attention a paper by G. G. Spellman and H. L. Nossel (Am. J. Physiol., 220: 922–927, 1971). They demonstrated that an extract from dog hookworm inhibited activated Factor X and platelet aggregation.






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Copyright © 1977 by the American Society of Tropical Medicine and Hygiene.