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Am. J. Trop. Med. Hyg., 26(5), 1977, pp. 1050
Copyright © 1977 by The American Society of Tropical Medicine and Hygiene

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The Biology of the Nocardiae

edited by M. GOODFELLOW, G. H. BROWNELL, and J. A. SERRANO. Academic Press, 111 Fifth Avenue, New York, New York 10003. 1976. No price

John R. Dooley
Armed Forces Institute of Pathology Washington, D.C. 20306

The major thrust of the book, including about 60% of the total pages, is concerned with newer information on the taxonomy of these organisms and, in particular, with their differentiation from such closely related taxa as mycobacteria, corynebacteria, actinomycetes and streptomycetes. Particular attention is given to the classification of those organisms traditionally denominated as Mycobacterium rhodochrous. The newer techniques applied to the solution of this and other taxonomic problems include chemical analysis of the cell wall, biochemistry of the intact cell, phage sensitivity, composition of nocobactins, serology, nucleic acid homology, and numerical taxonomy.

Other contributions detail studies on the use of intradermal sensitization tests as an aid in the taxonomy of the nocardiae and in the clinical recognition of illness caused by these organisms.

An important essay details pioneering studies on the ecology of nocardiae in nature and offers fragmentary information which may lead to a more comprehensive understanding of the way these organisms function in the biosphere and, possibly, of the way in which pathogenic nocardiae infect man and animals.







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Copyright © 1977 by the American Society of Tropical Medicine and Hygiene.