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Onchocerciasis: Invasion of Deep Organs by Onchocerca Volvulus

Autopsy Findings^*

Autopsies of two patients with onchocerciasis in the Republic of Zaïre are reported. In one patient with elephantiasis who died following diethylcarbamazine therapy there were large numbers of microfilariae of Onchocerca volvulus in the kidney, liver, pancreas, and lung. In the second patient, who also had leprosy and hyperinfection strongyloidiasis, we found an encapsulated adult O. volvulus in the wall of the thoracic aorta.

Accepted for publication December 6, 1976.

^* The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.

Address reprint requests to: Wayne M. Meyers, M.D., Ph.D., Department of Infectious and Parasitic Diseases Pathology, Armed Forces Institute of Pathology, Washington, D.C. 20306.