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Am. J. Trop. Med. Hyg., 25(5), 1976, pp. 663-666
Copyright © 1976 by The American Society of Tropical Medicine and Hygiene

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Seroepidemiology of Amebiasis in the Orang Asli (Western Malaysian Aborigine) and other Malaysians*

R. H. Gilman, C. Davis, E. Gan AND M. Bolton
Institute for Medical Research, Kuala Lumpur, Malaysia

The indirect hemagglutination test was used to study antibody titers to Entamoeba histolytica in different Malaysian populations. Eighty-seven percent of Orang Asli (western Malaysian aborigines) adults and 79% of Orang Asli children with acute amebic dysentery were seropositive. However, significantly fewer children (39%) with amebic dysentery had high titer responses (titer ≥1:1,280) than did adults with amebic dysentery (76%). No correlation between proctoscopic severity and amebic titer was found. Forty-four percent of asymptomatic family members were seroresponders. Satak, an Orang Asli village located near towns, had significantly more seroresponders (32%) than did the isolated, deep jungle village, Belatim (4%).

Accepted for publication March 6, 1976.


* Address reprint requests to: Robert H. Gilman, M.D., Division of Infectious Diseases, University of Maryland School of Medicine, 29 South Greene Street, Baltimore, Maryland 21201.




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Copyright © 1976 by the American Society of Tropical Medicine and Hygiene.