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Am. J. Trop. Med. Hyg., 25(3), 1976, pp. 432-436
Copyright © 1976 by The American Society of Tropical Medicine and Hygiene

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Schistosome Antigens in the Circulation of Chimpanzees Infected with Schistosoma Japonicum*

George V. Hillyer
Department of Biology, University of Puerto Rico, Rio Piedras, Puerto Rico

Chimpanzees infected with Schistosoma japonicum develop circulating schistosome antigens in their circulation between 6 and 9 weeks post-exposure. The minimum number of circulating antigens ranges from one to three. These antigens also cross-react with an antiserum against S. mansoni adult worms. Clearance of these antigens from the circulation several weeks later typically occurs. Persistence of these antigens could result in the observed renal damage.

Accepted for publication December 20, 1975.


* The chimpanzee sera were donated by Drs. Elvio H. Sadun and John I. Bruce, who made this study possible.






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Copyright © 1976 by the American Society of Tropical Medicine and Hygiene.