AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 25(2), 1976, pp. 351-352
Copyright © 1976 by The American Society of Tropical Medicine and Hygiene

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Plasmodium Brasilianum Antigen for use in the Indirect Hemagglutination Test

Henry M. Mathews AND Deborah A. Dilworth
Center for Disease Control, Public Health Service, U. S. Department of Health, Education, and Welfare, Atlanta, Georgia 30333

Antigen was prepared from Plasmodium brasilianum harvested from an infected spider monkey. This antigen was attached to aldehyde-fixed, human type O cells, and was tested against sera from human cases of P. malaria, P. vivax, P. falciparum, and P. ovale infection, and sera from noninfected persons. At dilutions of 1:16 or greater the antigen failed to react in sera from noninfected persons. It reacted at titers of 16 or above with sera from 85% of the persons with P. malariae infection, 83% with P. vivax infection, 70% with P. falciparum infection, and 70% with P. ovale infection.

Accepted for publication October 25, 1975.






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Copyright © 1976 by the American Society of Tropical Medicine and Hygiene.