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Am. J. Trop. Med. Hyg., 25(2), 1976, pp. 229-232
Copyright © 1976 by The American Society of Tropical Medicine and Hygiene

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Humoral Immunity of Parasitized, Malnourished Children*

David T. Purtilo, Randall S. Riggs, Richard Evans AND Ronald C. Neafie
Department of Pathology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01605, Department of Pathology, University of Washington Medical School, Seattle, Washington 98198, Walter Reed Army Medical Center, Washington, D. C. 10012, and Armed Forces Institute of Pathology, Washington, D. C. 20305

The nutrition, intensity of parasitism, complete blood count, and the serum immunoglobulin concentration of 63 children were studied. Hyperimmunoglobulinemia was present in the vast majority of subjects regardless of their nutritional status. The IgA and IgM concentrations were moderately increased, the IgG was increased threefold, and the IgE was markedly increased in concentration. The concentrations of the immunoglobulins were related significantly to the intensity of parasitism.

Accepted for publication January 4, 1975.


* The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.






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Copyright © 1976 by the American Society of Tropical Medicine and Hygiene.